Tightness not considered serious issue

McCaffrey is dealing with "tightness," but it doesn't seem to be an issue to worry about, Ian Rapoport of NFL Network reports.

For the sake of clarity, Rapoport emphasized that McCaffrey hasn't been missing practice due to a phantom injury or a contract hold-in. Rapoport suggested that the star running back is dealing with "actual tightness" as opposed to sitting out as a means of forcing contract negotiations, and the report also notes that McCaffrey "should be fine." At this point, fantasy managers can probably count on the workhorse tailback being available for Week 1 of the regular season, though it certainly bears monitoring his practice status as the preseason rolls on.

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More San Francisco 49ers Fantasy Football News

Confident he'll avoid PUP for Week 1

Kittle (Achilles) said Sunday that he's "very confident" he won't start the season on the reserve/PUP list and that he's still got a chance to play Week 1 versus the Rams, Nick Wagoner of ESPN.com reports.

Jordan James

RB SF

Not suiting up

James (ribs) will not play in Thursday's preseason opener against the Titans, Nick Wagoner of ESPN.com reports.

Mike Evans

Mike Evans

WR SF

Not suited up Thursday

Evans (quadriceps) is not dressed in uniform for Thursday night's preseason opener against the Titans, Nick Wagoner of ESPN.com reports.