Not suiting up
James (ribs) will not play in Thursday's preseason opener against the Titans, Nick Wagoner of ESPN.com reports.
James fractured his rib in late July and has still not recovered from the issue. The running back is set to be the primary relief back behind Christian McCaffrey (undisclosed), but if he can get healthy may see starting snaps depending on McCaffrey's outlook for the season. Running back Kaelon Black (thigh) is also not participating in Thursday's game, leaving Patrick Taylor, Sincere McCormick, Khalil Herbert and Zamir White to absorb all of Thursday's carries in an effort to climb a depth chart littered with injuries before cutdown day.
More San Francisco 49ers Fantasy Football News
Nick Bosa
Traveling with team to Australia
Bosa (knee) is making the trip to Australia and still could have a chance to play in the 49ers' Week 1 matchup against the Rams in Melbourne, Ian Rapoport of ESPN and NFL Network reports.
Mike Evans
Returns to practice Wednesday
Evans (groin) returned to practice Wednesday, Nick Wagoner of ESPN.com reports.
George Kittle
Traveling to Australia with team
Kittle (Achilles) will travel to Australia with the 49ers and "is trending in the right direction to play" in the season opener Sept. 10 versus the Rams, Ian Rapoport of NFL Network reports.
Christian McCaffrey
Goes through drills Tuesday
McCaffrey (undisclosed) suited up and went through drills at Tuesday's practice, according to Matt Lively of CBS Sports Bay Area.
Nick Bosa
Expected to practice Wednesday
Bosa (knee) worked to the side on the practice field Monday and is expected to do the same Tuesday, with a return to practice planned for Wednesday, Matt Maiocco of NBC Sports Bay Area reports.
George Kittle
Going through team drills
Kittle (Achilles) participated in practice Monday and plans to do so again Tuesday, David Lombardi of the San Francisco Standard reports.
Mike Evans
Eyeing practice return next week
49ers general manager John Lynch said Tuesday the team hopes to have Evans (groin) back at practice next week, David Lombardi of the San Francisco Standard reports.
George Kittle
Will be limited in practice this week
Kittle (Achilles) will be eased back into practice this week, Matt Barrows of The Athletic reports.
Christian Kirk
Placed on IR, designated to return
Kirk (calf) was placed on injured reserve by the 49ers on Sunday with a designation to return.
Isaac Guerendo
Lands on reserve/PUP list
Guerendo (pectoral) was placed on the reserve/PUP list, Jeremy Fowler of ESPN reports.