Quick start to preseason
Cook carried the ball five times for 21 yards in Saturday's 29-14 preseason win over the Panthers.
The reigning NFL rushing champ played the entire first quarter in the Bills' preseason opener, and Cook's longest gain was a 13-yard scamper that helped set up a Keon Coleman touchdown. Josh Allen remains the focal point of the offense, but Cook proved last season that he can rack up elite production as well, and the fifth-year RB could see more receiving work in 2026 as new offensive coordinator Pete Carmichael adds some wrinkles to Joe Brady's scheme.
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Ray Davis
Seven touches in preseason opener
Davis carried the ball three times for 21 yards and caught all four of his targets for 32 yards in Saturday's 29-14 preseason win over the Panthers.
Khalil Shakir
Two grabs in preseason opener
Shakir caught both his targets for 41 yards in Saturday's 29-14 preseason win over the Panthers.
Josh Allen
Finds end zone in preseason opener
Allen completed six of eight passes for 111 yards and a touchdown in Saturday's 29-14 preseason win over the Panthers.
Skyler Bell
Working through lower-body injury
Bell did not play in the Bills' 29-14 preseason win over the Panthers on Saturday due to a lower-body injury, Joe Buscaglia of The Athletic reports.
DJ Moore
Not worried about injury
Moore noted after Saturday's 29-14 preseason win over the Panthers that he was "good to go" after an apparent lower-body injury that he sustained in the first quarter, Joe Buscaglia of The Athletic reports.
DJ Moore
Limps off with possible ankle injury
Moore came off the field grabbing his ankle during Saturday's preseason game against the Panthers, Matt Parrino of The Syracuse Post-Standard reports.
Josh Allen
In line to play Saturday
Head coach Joe Brady said Thursday that Allen and the rest of Buffalo's healthy starters will play in Saturday's preseason opener against the Panthers, Maddy Glab of the Bills' official site reports.
Keon Coleman
Listed as starter on unofficial depth chart
Coleman is listed as a starter on Buffalo's first depth chart of the preseason, Lance Lysowski of The Buffalo News reports.
James Cook III
Could get more passing-game work
Bills offensive coordinator Pete Carmichael didn't rule out the possibility of Cook having more involvement as a pass catcher in 2026, Alex Brasky of SI.com reports. "Anytime you can get the ball in [Cook's] hands, you have an opportunity for a big play," Carmichael said Monday. "I think he can bring value not only in the run game but the pass game as well."
Josh Allen
Working well with Moore
Allen has been building chemistry with new WR DJ Moore early on in training camp, Alec White, Mike Maynard and Maddy Glab of the Bills' official site reports.