Monday Night Football DFS Slate Breakdown for Week 6

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With all of the craziness going on around the NFL, we get a rare doubleheader on Monday Night Football, and that means an additional DFS slate to build that bankroll! This article is unique for the DFS pass in that our structure generally provides cash and GPP picks for the main slate. However, a 2-game DFS slate is a whole different animal. Let’s start with some basic strategy before we break down my favorite plays.

In general, roster percentages are going to spike on a two-game slate given that the player pool shrinks with only four teams in action. As a result, we’re likely not going to be able to identify many players who are rostered on just 3-5% of teams the way we are in large-field tournaments on the main slate.

Because of this lack of variation in player pool selection, we need to be unique when building our GPP lineups from a roster construction standpoint. For example, it’s generally not recommended to play two TEs (one in the flex) in a DFS lineup as that has been shown to produce lower scores in most weeks and on most slates. However, in a two-game slate those types of contrarian roster builds are okay.

One final thing to consider when playing GPPs with a two-game slate is that our expectation of player production needs to be reduced relative to cost. A general rule of thumb that Kyle and I discuss on the DFS podcast when analyzing the main slate is that we’re looking for players who can 3x their salary in order to provide a spike week that’s needed to take down a GPP. Given that we’re forced to play thinner options, we can’t necessarily expect to have as many options to choose from for this type of scenario.

Week 6 MNF Schedule:
5 PM ET: Kansas City Chiefs @ Buffalo Bills, O/U: 57.0, KC -5
Implied Team Totals: KC: 30.75, BUF: 26.75
Injuries to monitor: John Brown (Questionable, knee), Dawson Knox (Out, calf), Sammy Watkins (Out, hamstring)
8:15 PM ET: Arizona Cardinals @ Dallas Cowboys, O/U: 55.0, ARI -2
Implied Team Totals: ARI: 28.25 , DAL: 26.75
Injuries to monitor: Chandler Jones (IR, Biceps)
Top Plays

Quarterbacks

Patrick Mahomes $7,500
As the best QB in football, there isn’t too much needed to justify Mahomes in cash games on a 2-game slate, but he finds himself in a smash spot against an underachieving Bills defense. They’ve conceded four straight top-14 fantasy finishes to opposing QBs, and from Weeks 2-5, the Bills have allowed a 9:1 TD-to-INT ratio. We can expect the Bills to also put up points in this one, which should help push this game into a shootout.

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