One catch in preseason debut
Samuel brought in one of two targets for four yards in the 49ers' 41-17 preseason win over the Chargers on Thursday night.
Samuel and the rest of the healthy 49ers offensive starters were out there for the team's opening possession, and the veteran wideout ended up recording his first catch in a San Francisco uniform since Week 17 of the 2024 season. His reception came on the Niners' first play from scrimmage, and the 30-year-old figures to play a prominent role in the air attack throughout the 2026 season alongside new No. 1 receiver Mike Evans (quadriceps) and fellow offseason addition Christian Kirk (calf).
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Kaelon Black
Logs eight carries in preseason win
Black rushed eight times for 33 yards and wasn't targeted in the 49ers' 41-17 preseason win over the Chargers on Thursday night.
De'Zhaun Stribling
Continues impressing in preseason win
Stribling secured four of five targets for 46 yards in the 49ers' 41-17 preseason win over the Chargers on Thursday.
Brock Purdy
Looks sharp in preseason win
Purdy completed four of six passes for 29 yards with no touchdowns or interceptions and rushed once for three yards in the 49ers' 41-17 preseason win over the Chargers on Thursday night.
George Kittle
Has chance to play Week 1
Kittle (Achilles) visited with Dr. Neal ElAttrache on Wednesday and remains ahead of schedule in his recovery with a chance to play Week 1 against the Rams, Adam Schefter of ESPN reports.
Christian McCaffrey
Not suited up for Thursday's game
McCaffrey (undisclosed) will not play in Thursday night's preseason game against the Chargers, David Lombardi of SFStandard.com reports.
Brock Purdy
'Good chance' to play in Thursday's contest
San Francisco coach Kyle Shanahan said Tuesday that Purdy has a "good chance" to play in Thursday's preseason matchup with the Chargers, Nick Wagoner of ESPN.com reports.
Christian McCaffrey
Coming along well, per Shanahan
Coach Kyle Shanahan said McCaffrey (undisclosed) would've practiced Tuesday if the 49ers hadn't been in a joint session with the Chargers, Nick Wagoner of ESPN.com reports.
Mike Evans
Injury issue downplayed by Shanahan
Coach Kyle Shanahan said after Tuesday's joint practice with the Chargers that Evans (quadriceps) experienced some tightness and doesn't believe the issue to be a serious one, Matt Maiocco of NBC Sports Bay Area reports.
Mike Evans
Slowed by left foot/ankle injury
Evans exited Tuesday's joint practice with the Chargers due to a left foot/ankle injury, Nick Wagoner of ESPN.com reports.
Kaelon Black
Returns to practice
Black (thigh) is back in uniform for Tuesday's practice session, Matt Barrows of The Athletic