Saquon Barkley, RB (PHI)

Not seen Wednesday

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Barkley (hamstring) wasn't spotted at the portion of Wednesday's practice open to the media, Jimmy Kempski of PhillyVoice.com reports.

Barkley was inactive for this past Sunday's loss to the Jaguars in London due to a hamstring injury suffered one week prior, but head coach Nick Sirianni told Zach Berman of The Athletic on Monday that he's "hopeful" the running back will gain clearance to play in Week 6 against the Panthers. Assuming Barkley goes down as a DNP on Wednesday, he's not beginning the week on the right foot, but he'll still have two more chances to mix into drills Thursday and Friday.

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DeVonta Smith

DeVonta Smith

WR PHI

Working on side Wednesday

Smith (hamstring) was working on the JUGS machine during Wednesday's practice, Olivia Reiner of The Philadelphia Inquirer reports.

DeVonta Smith

DeVonta Smith

WR PHI

Chance to return for Week 6

Head coach Nick Sirianni expressed hope Monday that Smith (hamstring) will return for this Sunday's game against the Panthers, Zach Berman of The Athletic reports.

Saquon Barkley

Saquon Barkley

RB PHI

Could return for Week 6

Head coach Nick Sirianni said Monday that he's "hopeful" that both Barkley (hamstring) and DeVonta Smith (hamstring) will both be cleared to play against the Panthers this coming Sunday, Zach Berman of The Athletic reports.

Will Shipley

RB PHI

Could face multi-week absence

Shipley (foot) was diagnosed with a partial tear of his plantar fascia after exiting Sunday's 19-17 loss to the Jaguars in London and could be sidelined multiple weeks, Adam Schefter of ESPN reports.

Jake Elliott

Jake Elliott

K PHI

Perfect in London

Elliott made his lone field-goal attempt and both of his extra-point tries during Sunday's 19-17 loss to the Jaguars in London.