Inactive versus Jets
Cook (toe) is inactive for Monday night's game against the Jets.
After being deemed a non-participant in Thursday's practice and Friday's walkthrough, Cook logged a limited session Saturday before being listed as questionable for the contest. With Cook having been made inactive by the Bills on Monday, look for Ty Johnson and Ray Davis to lead the team's Week 6 backfield, with practice-squad elevation Frank Gore also on hand to provide depth.
More Buffalo Bills Fantasy Football News
Keon Coleman
Listed as starter on unofficial depth chart
Coleman is listed as a starter on Buffalo's first depth chart of the preseason, Lance Lysowski of The Buffalo News reports.
James Cook III
Could get more passing-game work
Bills offensive coordinator Pete Carmichael didn't rule out the possibility of Cook having more involvement as a pass catcher in 2026, Alex Brasky of SI.com reports. "Anytime you can get the ball in [Cook's] hands, you have an opportunity for a big play," Carmichael said Monday. "I think he can bring value not only in the run game but the pass game as well."
Josh Allen
Working well with Moore
Allen has been building chemistry with new WR DJ Moore early on in training camp, Alec White, Mike Maynard and Maddy Glab of the Bills' official site reports.
Skyler Bell
Battling for game-day role
Joe Buscaglia of The Athletic relays that Bell's game-day role will be determined by his performances across the Bills' three preseason games.
Ty Johnson
Departs practice with knee injury
Johnson left practice early Saturday due to an apparent right knee injury, Matt Parrino of NYup.com reports.
Ray Davis
Returns after brief exit
Davis was able to check back into Tuesday's practice after briefly exiting with an apparent ankle injury, Matt Parrino of The Syracuse Post-Standard reports.
Dalton Kincaid
Resumes practicing after brief exit
Kincaid checked out of Monday's practice after he was slow to get up from a play during 11-on-11 drills, but he was able to return to the field for walkthroughs, Alaina Getzenberg of ESPN.com reports.
Tyler Bass
Recovered from injury
Bass noted Thursday that he's fully healthy after recovering from a pelvic injury that cost him the entire 2025 season, Matt Parrino of Syracuse.com reports.
James Cook III
More balanced approach in 2026?
New coach Joe Brady acknowledged this week that Cook's workload was high after the running back took 309 carries over 17 regular-season games, and the coach discussed the potential of sharing the load a bit more this season, Chris Brown of the Bills' official site reports. Said Brady, "I don't think you ever go into each game with a mindset of, 'This is how many carries he's going to have.' But it does pile up throughout the season, and I give him a lot of credit. I would love to be able to get Ray (Davis), Ty (Johnson), Frank (Gore Jr.) those guys involved and I hope those opportunities come up this year. James was just playing at such a high level last year. And this year again we're looking at everything."
James Cook III
Heads into Year 5 with Bills
During an appearance Tuesday on Good Morning Football, Cook indicated that he's noticed a renewed spirit under the guidance of new head coach Joe Brady during the team's offseason, Bobby Kownack of NFL.com reports.