Officially limited Thursday
McCaffrey (hamstring) was a limited participant at Thursday's practice, Sam Warren of The Athletic reports.
McCaffrey followed up Wednesday's lack of activity with some on-field work one day later, but he may need to practice fully Friday in order to avoid a designation for Sunday's game against the Raiders. He's tending to a left hamstring injury from a Week 7 loss in Atlanta, when he managed just a 52 percent snap share and churned out 100 yards from scrimmage and a rushing TD on 13 touches.
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Christian Kirk
Doesn't practice Thursday
Kirk (knee) didn't practice Thursday, Sam Warren of The Athletic reports.
Deebo Samuel Sr.
DNP on Thursday
Samuel (hamstring) was a non-participant at Thursday's practice, Sam Warren of The Athletic reports.
Mike Evans
No practice Thursday
Evans (Achilles) didn't participate in Thursday's practice, Sam Warren of The Athletic reports.
Deebo Samuel Sr.
Not spotted Thursday
Samuel (hamstring) did not participate in the portion of Thursday's practice open to the media, Nick Wagoner of ESPN.com reports.
Mike Evans
Misses open portion Thursday
Evans (Achilles) didn't participate in the portion of Thursday's practice open to the media, Nick Wagoner of ESPN.com reports.
Christian McCaffrey
Suited up for Thursday's practice
McCaffrey (hamstring) was present for the open portion of Thursday's practice, Nick Wagoner of ESPN reports.
Brandon Aiyuk
Path forward murky
Head coach Kyle Shanahan and GM John Lynch both declined to get into specifics when discussing the future of Aiyuk, who has filed his paperwork for reinstatement and plans to show up to the 49ers' facility Friday, Eric Branch of the San Francisco Chronicle reports.
Deebo Samuel Sr.
Not likely to play Sunday
According to GM John Lynch, Samuel (hamstring) is unlikely to be available for Sunday's game against the Raiders, Matt Maiocco of NBC Sports Bay Area reports.
Mike Evans
Likely to sit Sunday per GM
Evans (Achilles) isn't expected to play Sunday against the Raiders, 49ers GM John Lynch said on KNBR radio Thursday, Matt Maiocco of NBC Sports Bay Area reports.
Nick Bosa
Limited in practice Wednesday
Bosa (knee) was limited in Wednesday's practice, Sam Warren of The Athletic reports.