Accrues 141 total yards in loss
Cook rushed 24 times for 117 yards and brought in two of three targets for 24 yards in the Bills' 33-30 divisional-round overtime loss to the Broncos on Saturday. He also lost a fumble.
Cook put together an impressive day on the ground against an elite defense, finishing with his 10th 100-yard rushing performance since the start of the regular season and bouncing back in noteworthy fashion from his 46-yard effort versus the Jaguars in Sunday's wild-card victory. Cook's second-quarter lost fumble had a significant impact, however, as it came at the Broncos' 30-yard line and eventually led to a Denver touchdown. The disappointing team outcome aside, Cook's productive day Saturday was a fitting cap to a career-best regular season, one where he won the NFL rushing yardage title with 1,621 yards while averaging 5.2 yards per carry, scored 12 rushing touchdowns, and generated a 33-291-2 line on 40 targets while committing six fumbles, losing three, across 17 games.
More Buffalo Bills Fantasy Football News
DJ Moore
Settling in as Allen's top target
Quarterback Josh Allen said in late June that Moore has been "a pretty seamless fit" and is "going to be a huge help" for Buffalo's offense in 2026, Nick Shook of NFL.com reports.
Khalil Shakir
Set for key role once again
As his fifth season with Bills approaches, Shakir remains a key component of a WR corps that's been bolstered by offseason trade acquisition DJ Moore and rookie fourth-rounder Skyler Bell.
Joshua Palmer
Feeling healthy ahead of new season
After working off to the side during OTAs, Palmer (ankle) has been back as a participant during mandatory minicamp, Alec White and Maddy Glab of the Bills' official site report. "I'm feeling a lot better, starting to feel a lot more like myself," Palmer said after Wednesday's practice. "(I'm) close to pre-injury."
Ty Johnson
Past ankle injury
Johnson (ankle) is participating in OTAs, Jeffrey Barnes of the Bluefield Daily Telegraph reports.
James Cook III
Not present for start of OTAs
Cook was not present for the start of OTAs on Tuesday, Matt Parrino of Syracuse.com reports.
Joshua Palmer
Does side work during Day 2 of OTAs
Palmer (ankle) spent most of Tuesday's OTA session working to the side, Alaina Getzenberg of ESPN.com reports.
Dalton Kincaid
Has moved past knee issue
Kincaid (knee) was a participant in the Bills' OTAs on Tuesday, Sal Capaccio of WGR Sports Radio 550 Buffalo reports.
Josh Allen
Healthy for OTAs
Coach Joe Brady said Tuesday that Allen is "good to go" after the quarterback underwent foot surgery in the offseason, Sal Capaccio of WGR Sports Radio 550 Buffalo reports.
Keon Coleman
Has Joe Brady's support
Bills head coach Joe Brady said Tuesday that he advocated for Coleman this offseason and expects him to "be a part of our offense" in 2026, Sal Capaccio of WGR Sports Radio 550 Buffalo reports.
Keon Coleman
Garners support from front office
Bills GM Brandon Beane said Monday that the team has "hit the reset button" with Coleman and "thinks his best year is yet to come" during the 2026 season, Alaina Getzenberg of ESPN.com reports.