Dominates in win over Browns
Cook carried the ball 16 times for 117 yards and two touchdowns during Buffalo's 23-20 win over Cleveland on Sunday. He also secured one of two targets for 17 yards.
Cook has now surpassed 100 rushing yards in back-to-back games, as well as four of his last five appearances. He did much of his damage versus the Browns in the first half, scoring on a highlight-reel 44-yard run early in the first quarter, before finding pay dirt from three yards out late in the second quarter. Cook remains entrenched as the focal point of Buffalo's offense and is locked in as a high-end RB1 for fantasy purposes heading into a home matchup against the Eagles in Week 17. The Bills then will close out the regular season with a favorable home game against the Jets in Week 18.
More Buffalo Bills Fantasy Football News
James Cook III
Heads into Year 5 with Bills
During an appearance Tuesday on Good Morning Football, Cook indicated that he's noticed a renewed spirit under the guidance of new head coach Joe Brady during the team's offseason, Bobby Kownack of NFL.com reports.
Keon Coleman
Impressing new head coach
Coleman has impressed Buffalo's coaching staff with his offseason preparation and performance at minicamp, Alaina Getzenberg of ESPN.com reports.
DJ Moore
Settling in as Allen's top target
Quarterback Josh Allen said in late June that Moore has been "a pretty seamless fit" and is "going to be a huge help" for Buffalo's offense in 2026, Nick Shook of NFL.com reports.
Khalil Shakir
Set for key role once again
As his fifth season with Bills approaches, Shakir remains a key component of a WR corps that's been bolstered by offseason trade acquisition DJ Moore and rookie fourth-rounder Skyler Bell.
Joshua Palmer
Feeling healthy ahead of new season
After working off to the side during OTAs, Palmer (ankle) has been back as a participant during mandatory minicamp, Alec White and Maddy Glab of the Bills' official site report. "I'm feeling a lot better, starting to feel a lot more like myself," Palmer said after Wednesday's practice. "(I'm) close to pre-injury."
Ty Johnson
Past ankle injury
Johnson (ankle) is participating in OTAs, Jeffrey Barnes of the Bluefield Daily Telegraph reports.
James Cook III
Not present for start of OTAs
Cook was not present for the start of OTAs on Tuesday, Matt Parrino of Syracuse.com reports.
Joshua Palmer
Does side work during Day 2 of OTAs
Palmer (ankle) spent most of Tuesday's OTA session working to the side, Alaina Getzenberg of ESPN.com reports.
Dalton Kincaid
Has moved past knee issue
Kincaid (knee) was a participant in the Bills' OTAs on Tuesday, Sal Capaccio of WGR Sports Radio 550 Buffalo reports.
Josh Allen
Healthy for OTAs
Coach Joe Brady said Tuesday that Allen is "good to go" after the quarterback underwent foot surgery in the offseason, Sal Capaccio of WGR Sports Radio 550 Buffalo reports.