Stellar 160-yard effort not enough

McCaffrey rushed 22 times for 80 yards while corralling all eight of his targets for 80 yards and a touchdown in a 25-22 overtime loss to the Chiefs in Super Bowl LVIII.

McCaffrey's day got off to an ominous start when he fumbled away his fourth touch of the 49ers' opening drive in Kansas City territory. The NFL's Offensive Player of the Year responded by scoring the game's first touchdown on a trick play in the second quarter, finishing with game highs in yards (180) and touches (30) despite coming up short in overtime. CMC wraps up his first full season in San Francisco with 2,443 combined yards and 26 total touchdowns across 19 regular and postseason contests. Under contract through 2025, McCaffrey will head a retooled 49ers offense next year while likely being one of the first options taken off the boards in mock fantasy drafts.

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More San Francisco 49ers Fantasy Football News

Brandon Aiyuk

Brandon Aiyuk

WR | SF

Team seeking extension

49ers general manager John Lynch said Tuesday at the NFL Scouting Combine that the team wants to sign Aiyuk to a long-term contract extension, Eric Branch of the San Francisco Chronicle reports.

Deebo Samuel

Deebo Samuel

WR | SF

Powers through injury in OT loss

Samuel (hamstring) finished with three receptions (11 targets) for 33 yards while rushing three times for eight yards in Sunday's 25-22 overtime loss to the Chiefs.

Brock Purdy

Brock Purdy

QB | SF

Plays well in first SB appearance

Purdy completed 23 of 38 pass attempts for 255 yards and a touchdown while adding three carries for 12 yards in Sunday's 25-22 overtime loss to the Chiefs in Super Bowl LVIII.

Deebo Samuel

Deebo Samuel

WR | SF

Returns to Super Bowl

Samuel (hamstring) returned to Sunday's game against the Chiefs, Matt Maiocco of NBC Sports Bay Area reports.

Deebo Samuel

Deebo Samuel

WR | SF

Suffers hamstring injury

Samuel is questionable to return to Sunday's game against the Chiefs due to a hamstring injury, Ian Rapoport of NFL Network reports.

George Kittle

George Kittle

TE | SF

Set for Super Bowl

Kittle (toe) practiced fully Friday and doesn't have an injury designation for Super Bowl LVIII versus the Chiefs on Sunday.

Sam Darnold

Sam Darnold

QB | SF

Solid as backup in 2023

Darnold completed 61 percent of his pass attempts for 297 yards, two touchdowns and one interception across 10 games (one start) with San Francisco in 2023.