Gets back in end zone Sunday
McCaffrey carried the ball 21 times for 78 yards and caught all five of his targets for 25 yards and a touchdown in Sunday's 27-14 win over the Buccaneers.
After seeing his 17-game touchdown streak end last week, McCaffrey wasted little time starting a new one, snagging a four-yard score from Brock Purdy with just under four minutes left in the first quarter. He also topped 100 scrimmage yards for the third straight game and the seventh time in 10 contests this season, and McCaffrey's on pace to reach 2,000 scrimmage yards for the second time in his career. He could be poised for a big game in Week 12 against a Seahawks defense that just gave up 102 combined yards and a TD to the much less impressive duo of Royce Freeman and Darrell Henderson.
More San Francisco 49ers Fantasy Football News

George Kittle
TE | SF
Burns defenders for sixth TD
Kittle had three receptions on five targets for 76 yards and a touchdown in Sunday's 28-16 win over the Seahawks.

Brandon Aiyuk
WR | SF
Surpasses century mark
Aiyuk had six receptions on nine targets for 126 yards while also losing a fumble in Sunday's 28-16 win over Seattle.

Brock Purdy
QB | SF
Tops previous best with 368 yards
Purdy completed 19 of 27 pass attempts for 368 yards, two touchdowns and one interception while rushing twice for seven yards in Sunday's 28-16 win over Seattle.

Deebo Samuel
WR | SF
Two more scores in win
Samuel caught seven of nine targets for 149 yards and a touchdown while scoring another touchdown on his lone carry of one yard in Sunday's 28-16 win over Seattle.

Christian McCaffrey
RB | SF
Runs wild on Seahawks
McCaffrey took 16 carries for 145 yards and caught his lone target for eight yards in Sunday's 28-16 win over the Seahawks.
Jordan Mason
RB | SF
Should serve as No. 2 back
Mason is in line to serve as the No. 2 running back for Sunday's Week 14 game against the Seahawks with Elijah Mitchell (knee) ruled inactive for the contest.

Elijah Mitchell
RB | SF
Officially inactive Sunday
Mitchell (knee) is inactive for Sunday's Week 14 clash with Seattle.

Elijah Mitchell
RB | SF
Doubtful after missed practices
Mitchell (knee) is listed as doubtful for Sunday's game against Seattle, Matt Barrows of The Athletic reports.

Ray-Ray McCloud III
WR | SF
Sitting out second straight game
The 49ers have ruled McCloud out in advance of Sunday's game against the Seahawks, Matt Barrows of The Athletic reports.

Elijah Mitchell
RB | SF
No practice Thursday
Mitchell (knee) didn't practice Thursday, Josh Dubow of The Associated Press reports.