Plays through shoulder injury
Head coach Kyle Shanahan announced that Aiyuk suffered a shoulder injury in Sunday's win over the Rams that limited his playing time, according to 49ers' team reporter Lindsey Pallares.
Aiyuk was able to finish the game and post a final line of three catches on six targets for 43 yards. The 25-year-old suffered the shoulder injury in the first quarter and was seen being worked on by trainers at various points of contest. Aiyuk didn't appear limited when he would return to action, which is a positive sign for his availability moving forward. That said, it wouldn't be surprising to see Aiyuk's name pop up on the injury report with a Thursday matchup against the Giants on tap for Week 3.
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Deebo Samuel
WR | SF
Expected to suit up Sunday
Samuel (knee) is expected to play Sunday versus the Cardinals, Adam Schefter of ESPN reports.

Jauan Jennings
WR | SF
Unlikely to play Sunday
Jennings (shin) is listed as doubtful for Sunday's game against the Cardinals.

Elijah Mitchell
RB | SF
Gets questionable tag for Sunday
Mitchell is listed as questionable for Sunday's game against the Cardinals after he was a non-participant in Friday's practice due to a knee injury.

Brandon Aiyuk
WR | SF
Good to go for Week 4
Aiyuk (shoulder) doesn't have an injury designation for Sunday's game against the Cardinals, Matt Barrows of The Athletic reports.

Deebo Samuel
WR | SF
Deemed questionable for Week 4
Samuel (knee/ribs) is listed as questionable for Sunday's game against the Cardinals, Matt Barrows of The Athletic reports.

Deebo Samuel
WR | SF
Limited to side work
Samuel (ribs/knee) is running on the side during Friday's practice, Nick Wagoner of ESPN.com reports.

Brandon Aiyuk
WR | SF
Remains limited Thursday
Aiyuk (shoulder) was a limited participant at Thursday's practice, Nick Wagoner of ESPN.com reports.

Deebo Samuel
WR | SF
Another DNP on Thursday
Samuel (ribs/knee) officially didn't practice Thursday, Nick Wagoner of ESPN.com reports.

Deebo Samuel
WR | SF
Not practicing Thursday
Samuel (ribs) wasn't participating at the beginning of Thursday's practice, Nick Wagoner of ESPN.com reports.

Brandon Aiyuk
WR | SF
Sheds non-contact jersey Thursday
Aiyuk (shoulder) wasn't wearing a non-contact jersey at the start of Thursday's practice, Cam Inman of The San Jose Mercury News reports.