Confirmed for lead role Sunday
Williams will serve as the Rams' lead back for Sunday's game against the 49ers, a source told Jeremy Fowler of ESPN.com.
The Rams will make Cam Akers inactive for the contest and could look into trading him away after he managed just 29 yards on 22 carries while playing 33 percent of the offensive snaps in Los Angeles' season-opening win over Seattle. Williams, who worked behind Akers in Week 1 but played 67 percent of snaps and finished with 15 carries for 52 yards and two touchdowns while also drawing two targets, should now get a chance to build on that performance. Though the matchup with a stingy San Francisco defense isn't an ideal one for fantasy purposes, Williams' season-long outlook should see a big boost if Akers remains out of the backfield mix in the weeks to come.
More Los Angeles Rams Fantasy Football News
Puka Nacua
WR | LAR
Not practicing Thursday
Coach Sean McVay said Nacua (oblique) won't take part in Thursday's practice, Adam Grosbard of The Orange County Register reports.

Tyler Higbee
TE | LAR
Minimal impact in loss
Higbee secured three of seven targets for 12 yards during Sunday's 30-23 loss to the 49ers.

Van Jefferson
WR | LAR
Forgettable day with one catch
Jefferson secured one of four targets for nine yards during Sunday's 30-23 loss to the 49ers.

Tutu Atwell
WR | LAR
Goes for 82 total yards
Atwell had seven receptions on nine targets for 77 yards while adding five yards on a rushing attempt in Sunday's 30-23 loss to San Francisco.

Matthew Stafford
QB | LAR
Costly interceptions Sunday
Stafford completed 34 of 55 pass attempts for 307 yards, a touchdown and two interceptions in Sunday's 30-23 loss to the 49ers.

Kyren Williams
RB | LAR
Leads backfield with two-score day
Williams rushed 14 times for 52 yards and a touchdown while adding six receptions (10 targets) for 48 yards and another score in Sunday's 30-23 loss to the 49ers.
Puka Nacua
WR | LAR
Impressive follow-up performance
Nacua (oblique) caught 15 of 20 targets for 147 yards and no touchdowns while adding four yards on two carries in Sunday's 30-23 loss to the 49ers.
Puka Nacua
WR | LAR
Suits up Sunday
Nacua (oblique) is listed as active for Sunday's game against the 49ers.

Kyren Williams
RB | LAR
Could handle lead role Sunday
Williams is expected to serve as the Rams' lead back Sunday against the 49ers after Jay Glazer reported on "Fox NFL Sunday" that Cam Akers will be a healthy inactive for the contest.
Puka Nacua
WR | LAR
Questionable to face 49ers
Nacua (oblique) is listed as questionable for Sunday's game against the 49ers after returning to a limited practice Friday.