Kyren Williams, RB (LAR)

Confirmed for lead role Sunday

Williams will serve as the Rams' lead back for Sunday's game against the 49ers, a source told Jeremy Fowler of ESPN.com.

The Rams will make Cam Akers inactive for the contest and could look into trading him away after he managed just 29 yards on 22 carries while playing 33 percent of the offensive snaps in Los Angeles' season-opening win over Seattle. Williams, who worked behind Akers in Week 1 but played 67 percent of snaps and finished with 15 carries for 52 yards and two touchdowns while also drawing two targets, should now get a chance to build on that performance. Though the matchup with a stingy San Francisco defense isn't an ideal one for fantasy purposes, Williams' season-long outlook should see a big boost if Akers remains out of the backfield mix in the weeks to come.

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More Los Angeles Rams Fantasy Football News

Puka Nacua

WR | LAR

Not practicing Thursday

Coach Sean McVay said Nacua (oblique) won't take part in Thursday's practice, Adam Grosbard of The Orange County Register reports.

Tutu Atwell

Tutu Atwell

WR | LAR

Goes for 82 total yards

Atwell had seven receptions on nine targets for 77 yards while adding five yards on a rushing attempt in Sunday's 30-23 loss to San Francisco.

Puka Nacua

WR | LAR

Impressive follow-up performance

Nacua (oblique) caught 15 of 20 targets for 147 yards and no touchdowns while adding four yards on two carries in Sunday's 30-23 loss to the 49ers.

Kyren Williams

Kyren Williams

RB | LAR

Could handle lead role Sunday

Williams is expected to serve as the Rams' lead back Sunday against the 49ers after Jay Glazer reported on "Fox NFL Sunday" that Cam Akers will be a healthy inactive for the contest.

Puka Nacua

WR | LAR

Questionable to face 49ers

Nacua (oblique) is listed as questionable for Sunday's game against the 49ers after returning to a limited practice Friday.