Slated to work alongside Cook
Following the 2023 NFL Draft, Harris is in line to work in a Buffalo backfield that also includes James Cook, Nyheim Hines and Latavius Murray, Alaina Getzenberg of ESPN.com reports.
Given that last season's top rusher Devin Singletary is now with the Texans, the Bills backfield is in transition, with both Getzenberg and Joe Buscaglia of The Athletic indicating that Cook, a 2022 second-rounder, is expected to have an opportunity to carve out a lead role in 2023. That said, as long as Harris remains healthy, he'll have a chance to absorb a decent share of early-down and short-yardage touches, with Hines on hand as a change-of-pace option and Murray providing another early-down option in the event that Cook or Harris miss any time. Additionally, the team gained further RB depth after the draft by signing UDFA Jordan Mims.
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Dawson Knox
TE | BUF
Practices fully, slated to play
Knox (back) practiced in full Friday and doesn't have an injury designation ahead of Sunday's Week 3 game against the Commanders.

James Cook
RB | BUF
Back at practice
Cook (personal) returned to practice Friday, Alaina Getzenberg of ESPN.com reports.

Dawson Knox
TE | BUF
Returning to practice
Knox (back) is in line to practice Friday, Alaina Getzenberg of ESPN.com reports.

James Cook
RB | BUF
Absent for personal reason
Cook missed Thursday's practice due to a personal matter, Chris Brown of the Bills' official site reports.

James Cook
RB | BUF
Not spotted at practice
Cook (undisclosed) wasn't spotted during the open portion of Thursday's practice, Alaina Getzenberg of ESPN.com reports.

Dawson Knox
TE | BUF
Not practicing again
Knox (back) won't practice Thursday, Katherine Fitzgerald of The Buffalo News reports.

Dawson Knox
TE | BUF
Not practicing Wednesday
Knox won't practice Wednesday due to a back injury, Chris Brown of the Bills' official site reports.

Trent Sherfield
WR | BUF
Uninvolved offensively
Sherfield has yet to be targeted through two games even though he's seen 39 snaps on offense.

Khalil Shakir
WR | BUF
Scores in romp over Raiders
Shakir caught his only target for 11 yards and a touchdown in Sunday's 38-10 win over the Raiders.

Latavius Murray
RB | BUF
Works ahead of Harris
Murray carried the ball six times for 22 yards and one touchdown in Sunday's 38-10 win over the Raiders. He added two receptions on two targets for nine yards.