Nursing ankle injury
Samuel won't practice Wednesday due to an ankle injury, Nick Wagoner of ESPN.com reports.
Samuel played 60 of the 49ers' 66 offensive snaps during the divisional-round win over Dallas, but he failed to make any splash plays as the offense was stymied by the Cowboys' athletic defense. The star wideout didn't appear to have gotten injured at any point during the contest, so his absence from practice Wednesday due to the ankle issue may just be maintenance-related after he missed Weeks 15 through 17 with an ankle sprain as well as an MCL sprain. Assuming Samuel is able to get back on the field for practice in some capacity by Friday, he should be in good shape to play in Sunday's NFC Championship Game against the Eagles, per Eric Branch of the San Francisco Chronicle.
More San Francisco 49ers Fantasy Football News

Brandon Aiyuk
WR | SF
Held to one catch in loss
Aiyuk caught his lone target for 10 yards in Sunday's 31-7 NFC Championship Game loss to the Eagles.
Brock Purdy
QB | SF
Suffers elbow injury in loss
Purdy (elbow) suffered an injury to his right throwing arm early in Sunday's 31-7 playoff loss to the Eagles, resulting in four completed passes for 23 yards and one fumble lost.
Brock Purdy
QB | SF
Likely out at least six weeks
Purdy (elbow) is believed to have injured his ulnar collateral ligament in Sunday's 31-7 NFC Championship Game loss to the Eagles and will have an MRI on the injury Monday, Adam Schefter of ESPN.com reports.

George Kittle
TE | SF
Catches three balls in playoff loss
Kittle caught three of four targets for 32 yards in Sunday's 31-7 NFC Championship Game loss to Philadelphia.

Deebo Samuel
WR | SF
Struggles in NFCCG loss
Samuel caught three of six targets for 33 yards and rushed six times for a loss of nine yards (one fumble lost) in Sunday's 31-7 playoff loss to the Eagles.

Christian McCaffrey
RB | SF
Lone bright spot on offense
McCaffrey (calf) rushed 15 times for 84 yards and a touchdown while catching all four of his targets for 22 yards in Sunday's 31-7 playoff loss to the Eagles.

Josh Johnson
QB | SF
Won't return to Sunday's game
Johnson (concussion) won't return to Sunday's NFC Championship Game against the Eagles.
Brock Purdy
QB | SF
Back in Sunday's game
Purdy, who had been forced out of Sunday's NFC Championship Game against the Eagles with a right elbow injury, subsequently returned to the contest.

Josh Johnson
QB | SF
Evaluated for concussion
Johnson is being evaluated for a concussion during Sunday's NFC Championship Game against the Eagles.
Brock Purdy
QB | SF
Exits Sunday's game
Purdy was forced out of Sunday's NFC Championship Game against the Eagles with a right elbow injury.