Remains limited by knee issue

McCaffrey was limited in practice Wednesday due to a knee injury, Eric Branch of the San Francisco Chronicle reports.

McCaffrey endured practice limitations last week with the same health concern, but he eventually ditched a designation on the final Week 13 injury report. He proceeded to have his second-most touches (25) in a 49ers uniform en route to 146 yards from scrimmage and a receiving TD this past Sunday against the Dolphins. Assuming he gets through this week unscathed, too, McCaffrey will be set to dominate the backfield work for the team Sunday versus the Buccaneers.

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Jimmy Garoppolo

Jimmy Garoppolo

QB | SF

Super Bowl return still possible

Garoppolo (foot) has already been ruled out for Sunday's NFC Championship Game, but the quarterback left the possibility open of returning for the Super Bowl if the 49ers advance, Matt Barrows of The Athletic reports.

Jimmy Garoppolo

Jimmy Garoppolo

QB | SF

Not returning Sunday

Garoppolo (foot) has been ruled out for Sunday's NFC Championship Game at Philadelphia, Matt Maiocco of NBC Sports Bay Area reports.

Deebo Samuel

Deebo Samuel

WR | SF

Clear to play Sunday

Samuel (ankle) doesn't have a designation for Sunday's NFC Championship Game at Philadelphia, Matt Maiocco of NBC Sports Bay Area reports.

Ready for Sunday

McCaffrey (calf) doesn't have a designation for Sunday's NFC Championship Game in Philadelphia, David Lombardi of The Athletic reports.

Elijah Mitchell

Elijah Mitchell

RB | SF

Not on field Friday

Mitchell (groin) wasn't spotted during the media-access portion of Friday's practice, David Lombardi of The Athletic reports.

Expects to play Sunday

McCaffrey (calf), who didn't practice Thursday, told Matt Maiocco of NBC Sports Bay Area that there's "zero" chance that he doesn't play in Sunday's NFC Championship Game in Philadelphia.

Deebo Samuel

Deebo Samuel

WR | SF

Another limited practice

Coach Kyle Shanahan said Samuel (ankle) will be limited at Thursday's practice, Matt Maiocco of NBC Sports Bay Area reports.