Managing knee issue
McCaffrey will be managed day-to-day, as the running back is dealing with what coach Kyle Shanahan has described as knee irritation, Nick Wagoner of ESPN.com reports.
At this stage, there's nothing to suggest that McCaffrey is in danger of missing Sunday's game against the Dolphins, but it appears as though his practice reps will be managed this week. With Elijah Mitchell slated to miss 6-to-8 weeks with an MCL injury, McCaffrey is in line to continue to lead the 49ers' ground game in the coming weeks, with Jordan Mason and Tyrion Davis-Price set to work in change-of-pace/complementary roles and Tevin Coleman a candidate to be promoted from the team's practice squad.
More San Francisco 49ers Fantasy Football News

Trey Lance
QB | SF
Will be 100 percent for OTAs
Lance (ankle) said Tuesday that he's 3-4 weeks away from being cleared for practice and will be 100 percent for OTAs this summer, Matt Barrows of The Athletic reports.
Brock Purdy
QB | SF
Tears UCL, set for surgery
Purdy is slated for surgery on his right elbow after suffering a complete tear of his UCL during Sunday's NFC Championship Game loss at Philadelphia, and the 49ers hope he'll be healthy by training camp, Tom Pelissero of NFL Network reports.

Brandon Aiyuk
WR | SF
Held to one catch in loss
Aiyuk caught his lone target for 10 yards in Sunday's 31-7 NFC Championship Game loss to the Eagles.
Brock Purdy
QB | SF
Suffers elbow injury in loss
Purdy (elbow) suffered an injury to his right throwing arm early in Sunday's 31-7 playoff loss to the Eagles, resulting in four completed passes for 23 yards and one fumble lost.
Brock Purdy
QB | SF
Likely out at least six weeks
Purdy (elbow) is believed to have injured his ulnar collateral ligament in Sunday's 31-7 NFC Championship Game loss to the Eagles and will have an MRI on the injury Monday, Adam Schefter of ESPN.com reports.

George Kittle
TE | SF
Catches three balls in playoff loss
Kittle caught three of four targets for 32 yards in Sunday's 31-7 NFC Championship Game loss to Philadelphia.

Deebo Samuel
WR | SF
Struggles in NFCCG loss
Samuel caught three of six targets for 33 yards and rushed six times for a loss of nine yards (one fumble lost) in Sunday's 31-7 playoff loss to the Eagles.

Christian McCaffrey
RB | SF
Lone bright spot on offense
McCaffrey (calf) rushed 15 times for 84 yards and a touchdown while catching all four of his targets for 22 yards in Sunday's 31-7 playoff loss to the Eagles.

Josh Johnson
QB | SF
Won't return to Sunday's game
Johnson (concussion) won't return to Sunday's NFC Championship Game against the Eagles.
Brock Purdy
QB | SF
Back in Sunday's game
Purdy, who had been forced out of Sunday's NFC Championship Game against the Eagles with a right elbow injury, subsequently returned to the contest.