Deebo Samuel, WR (SF)

Listed as limited again

Samuel (hamstring) was listed as limited on Thursday's practice report, Josh Dubow of The Associated Press reports.

Since being inactive Week 8 due to a hamstring issue, Samuel has made back-to-back appearances following the 49ers' Week 9 bye, combining for 145 yards from scrimmage and one rushing TD on 16 touches. His snap share (58 percent) was impacted Week 11 only by the fact that the team was in the midst of blowing out the Cardinals, so his practice limitations Wednesday and Thursday could be maintenance-related with the rest of the campaign in mind. Friday's report may provide some clarity regarding Samuel's status ahead of Sunday's outing against the Saints.

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Brock Purdy

QB | SF

Takes over for injured starter

Purdy completed 25 of 37 pass attempts for 210 yards, two touchdowns and an interception in relief of Jimmy Garoppolo (foot) in Sunday's 33-17 win over Miami.

Deebo Samuel

Deebo Samuel

WR | SF

Gains 63 yards on 10 touches

Samuel (quadriceps) had six receptions on 10 targets for 58 yards and rushed four times for five yards in Sunday's 33-17 win over the Dolphins.

Carries offense in big win

McCaffrey (knee) carried the ball 17 times for 66 yards while adding eight receptions on 10 targets for 80 yards and a touchdown in Sunday's 33-17 win over the Dolphins.

Jimmy Garoppolo

Jimmy Garoppolo

QB | SF

Ruled out for season

Garoppolo sustained a broken foot Sunday against the Dolphins and will miss the remainder of the season, Nick Wagoner of ESPN.com reports.