Brandon Aiyuk, WR (SF)

Makes most of minimal targets

Aiyuk recorded two receptions on four targets for 20 yards and two touchdowns in Monday's 38-10 win over the Cardinals.

Aiyuk saw his lowest target total since Week 5, as each of Christian McCaffrey, Deebo Samuel and George Kittle played a more prominent role in the passing attack. Even so, Aiyuk managed a strong fantasy performance by tallying touchdowns on each of his receptions from seven and 13 yards away, respectively. Aiyuk now has five touchdowns across his last five games, and he's also topped 80 receiving yards on four occasions in that span.

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More San Francisco 49ers Fantasy Football News

Brock Purdy

QB | SF

Takes over for injured starter

Purdy completed 25 of 37 pass attempts for 210 yards, two touchdowns and an interception in relief of Jimmy Garoppolo (foot) in Sunday's 33-17 win over Miami.

Deebo Samuel

Deebo Samuel

WR | SF

Gains 63 yards on 10 touches

Samuel (quadriceps) had six receptions on 10 targets for 58 yards and rushed four times for five yards in Sunday's 33-17 win over the Dolphins.

Carries offense in big win

McCaffrey (knee) carried the ball 17 times for 66 yards while adding eight receptions on 10 targets for 80 yards and a touchdown in Sunday's 33-17 win over the Dolphins.

Jimmy Garoppolo

Jimmy Garoppolo

QB | SF

Ruled out for season

Garoppolo sustained a broken foot Sunday against the Dolphins and will miss the remainder of the season, Nick Wagoner of ESPN.com reports.