Out at least four games
The Broncos placed Gregory (knee) on injured reserve Tuesday, Aric DiLalla of the team's official site reports.
Gregory exited in the fourth quarter of Sunday's loss to the Raiders due to the right knee injury, and though follow-up tests cleared him of any damage to his ACL, he'll still require an arthroscopic procedure to trim his meniscus. A typical recovery timeline associated with procedure is 2-to-4 weeks, but Gregory's move to IR ensures he'll have five weeks to recover. Gregory will be forced to miss at least four games due to the move to IR, and because the Broncos are on bye Week 9, the pass rusher won't be eligible to play until Denver's Week 10 game Nov. 13 in Tennessee. Baron Browning is expected to move into a starting role at outside linebacker opposite Bradley Chubb while Gregory is sidelined.
More San Francisco 49ers Fantasy Football News
49ers general manager John Lynch said Tuesday at the NFL Scouting Combine that the team wants to sign Aiyuk to a long-term contract extension, Eric Branch of the San Francisco Chronicle reports.
Kittle caught two of three targets for four yards in Sunday's 25-22 overtime loss to the Chiefs in Super Bowl LVIII.
Aiyuk had three receptions on six targets for 49 yards in a 25-22 overtime loss to the Chiefs in Super Bowl LVIII.
Samuel (hamstring) finished with three receptions (11 targets) for 33 yards while rushing three times for eight yards in Sunday's 25-22 overtime loss to the Chiefs.
Purdy completed 23 of 38 pass attempts for 255 yards and a touchdown while adding three carries for 12 yards in Sunday's 25-22 overtime loss to the Chiefs in Super Bowl LVIII.
McCaffrey rushed 22 times for 80 yards while corralling all eight of his targets for 80 yards and a touchdown in a 25-22 overtime loss to the Chiefs in Super Bowl LVIII.
Samuel (hamstring) returned to Sunday's game against the Chiefs, Matt Maiocco of NBC Sports Bay Area reports.
Samuel is questionable to return to Sunday's game against the Chiefs due to a hamstring injury, Ian Rapoport of NFL Network reports.
Kittle (toe) practiced fully Friday and doesn't have an injury designation for Super Bowl LVIII versus the Chiefs on Sunday.
Darnold completed 61 percent of his pass attempts for 297 yards, two touchdowns and one interception across 10 games (one start) with San Francisco in 2023.