Out for a third straight game
Jefferson (knee) didn't practice Friday and won't play in Sunday's game against the Cardinals, Josh Weinfuss of ESPN.com reports.
The third-year pro still hasn't practiced since having minor knee surgery in early August, but his role as the No. 3 receiver appears fairly safe given the lack of production behind Cooper Kupp so far. Ben Skowronek, filling in as the No. 3, has managed only six catches for 41 yards on nine targets in two games, playing 88 and 86 percent of snaps on offense. Jefferson should be more of a threat if/when he moves past the knee surgery and reclaims his role. The lack of practice reps suggests that's unlikely to happen for Week 4 at San Francisco, though the Rams haven't officially ruled him out beyond Week 3.
More Los Angeles Rams Fantasy Football News
Puka Nacua
WR | LAR
Gets questionable tag
Although Nacua (oblique) has been given a questionable designation for Monday's matchup with the Bengals, head coach Sean McVay "expects him to play," Adam Grosbard of The Orange County Register reports.
Puka Nacua
WR | LAR
Returns as limited participant
Nacua (oblique) practiced on a limited basis Friday, Adam Caplan of SiriusXM NFL Radio reports.
Puka Nacua
WR | LAR
Not practicing Thursday
Coach Sean McVay said Nacua (oblique) won't take part in Thursday's practice, Adam Grosbard of The Orange County Register reports.

Tyler Higbee
TE | LAR
Minimal impact in loss
Higbee secured three of seven targets for 12 yards during Sunday's 30-23 loss to the 49ers.

Van Jefferson
WR | LAR
Forgettable day with one catch
Jefferson secured one of four targets for nine yards during Sunday's 30-23 loss to the 49ers.

Tutu Atwell
WR | LAR
Goes for 82 total yards
Atwell had seven receptions on nine targets for 77 yards while adding five yards on a rushing attempt in Sunday's 30-23 loss to San Francisco.

Matthew Stafford
QB | LAR
Costly interceptions Sunday
Stafford completed 34 of 55 pass attempts for 307 yards, a touchdown and two interceptions in Sunday's 30-23 loss to the 49ers.

Kyren Williams
RB | LAR
Leads backfield with two-score day
Williams rushed 14 times for 52 yards and a touchdown while adding six receptions (10 targets) for 48 yards and another score in Sunday's 30-23 loss to the 49ers.
Puka Nacua
WR | LAR
Impressive follow-up performance
Nacua (oblique) caught 15 of 20 targets for 147 yards and no touchdowns while adding four yards on two carries in Sunday's 30-23 loss to the 49ers.

Kyren Williams
RB | LAR
Confirmed for lead role Sunday
Williams will serve as the Rams' lead back for Sunday's game against the 49ers, a source told Jeremy Fowler of ESPN.com.