Trey Lance, QB (SF)

Heads to injured reserve

The 49ers placed Lance (ankle) on injured reserve Wednesday

This transaction was inevitable after Lance broke his right fibula and suffered a ligament disruption in his right ankle Week 2 against the Seahawks. The second-year signal-caller already underwent season-ending surgery Monday, and he's expected to remain in San Francisco for the entirety of his rehab with the anticipation that he'll return to full health for the 2023 season. In Lance's stead, Jimmy Garoppolo has retaken the reins of the 49ers offense, with Brock Purdy serving as the team's No. 2 quarterback.

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Jauan Jennings

Jauan Jennings

WR | SF

Battling ankle injury

San Francisco head coach Kyle Shanahan said Jennings is day-to-day after suffering an ankle injury in Monday's 24-9 win over the Rams, Josh Dubow of The Associated Press reports.