Heads to injured reserve
The 49ers placed Lance (ankle) on injured reserve Wednesday
This transaction was inevitable after Lance broke his right fibula and suffered a ligament disruption in his right ankle Week 2 against the Seahawks. The second-year signal-caller already underwent season-ending surgery Monday, and he's expected to remain in San Francisco for the entirety of his rehab with the anticipation that he'll return to full health for the 2023 season. In Lance's stead, Jimmy Garoppolo has retaken the reins of the 49ers offense, with Brock Purdy serving as the team's No. 2 quarterback.
More San Francisco 49ers Fantasy Football News
San Francisco head coach Kyle Shanahan said Jennings is day-to-day after suffering an ankle injury in Monday's 24-9 win over the Rams, Josh Dubow of The Associated Press reports.
Aiyuk caught all four of his targets for 37 yards in Monday's 24-9 win over the Rams.
Garoppolo completed 16 of 27 passes for 239 yards and one touchdown in Monday's 24-9 win over the Rams. He added three yards on one rushing attempt.
Kittle caught two of four targets for 24 yards in Monday's 24-9 win over the Rams.
Wilson rushed 18 times for 74 yards and a touchdown but wasn't targeted in Monday's 24-9 win over the Rams.
Samuel caught six of seven targets for 115 yards and a touchdown in Monday's 24-9 win over the Rams. He added two yards on two rushing attempts.
Coleman has been elevated from the 49ers' practice squad ahead of Monday night's game against the Rams.
Gray didn't practice Thursday due to a hip issue, Eric Branch of the San Francisco Chronicle reports.
Mack was only on the field for three special teams snaps in Sunday's 11-10 loss to Denver.
Mason received one carry for seven yards in Sunday's 11-10 loss to Denver.