Set for season-ending surgery
Head coach Kyle Shanahan said Lance suffered a broken right ankle in Sunday's win over the Seahawks and will undergo season-ending surgery Monday, Eric Branch of the San Francisco Chronicle reports.
Fears of a season-ending injury immediately circulated when Lance was carted off the field in the first quarter of Sunday's contest, and Shanahan confirmed hours later that the second-year quarterback won't play again in 2022. Jimmy Garoppolo replaced the injured Lance and helped lead the 49ers to a 27-7 win. It's a tough setback for Lance in just the second game of his first season as a starter, after he often watched from the sidelines as Garoppolo's understudy during his rookie season.
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Mack was only on the field for three special teams snaps in Sunday's 11-10 loss to Denver.
Mason received one carry for seven yards in Sunday's 11-10 loss to Denver.
Jennings had one reception (three targets) for five yards in Sunday's 11-10 loss to Denver.
Aiyuk caught three of eight targets for 39 yards and a touchdown in Sunday's 11-10 loss to the Broncos.
Kittle (groin) hauled in four of five targets for 28 yards in Sunday's 11-10 loss to the Broncos.
Wilson rushed 12 times for 75 yards while adding three receptions for 31 yards in Sunday's 11-10 loss to Denver.
Samuel caught five of eight targets for 73 yards and rushed five times for six yards in Sunday's 11-10 loss to Denver.
Kittle (groin) has been cleared for Sunday's game against Denver, avoiding a designation on the 49ers' final injury report, Nick Wagoner of ESPN.com reports.
Kittle (groin) was limited at practice Thursday, Matt Maiocco of NBC Sports Bay Area reports.
Head coach Kyle Shanahan said Kittle (groin) will be a limited practice participant Wednesday, Nick Wagoner of ESPN.com reports.