Deebo Samuel, WR (SF)

No practice Wednesday

Samuel (groin) didn't practice Wednesday, Eric Branch of the San Francisco Chronicle reports.

With a 1-to-2-game absence imminent due to a groin strain, Samuel likely will log DNPs all week before the 49ers rule him out for Sunday's contest at Seattle. In his absence, the 49ers will rely on Brandon Aiyuk, Jauan Jennings, Trent Sherfield and Travis Benjamin at wide receiver, while River Cracraft and Connor Wedington are candidates to be elevated from the practice squad for game day.

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Danny Gray

WR | SF

Full practice Wednesday

Gray (hip/back) returned to a full practice during Wednesday's joint session with the Vikings, Matt Barrows of The Athletic reports.

Trey Sermon

Trey Sermon

RB | SF

Inefficient in preseason win

Sermon rushed six times for 11 yards and brought in his only target for five yards in the 49ers' 28-21 preseason win over the Packers on Friday night.

Elijah Mitchell

Elijah Mitchell

RB | SF

Not playing preseason Week 2

Mitchell (hamstring) isn't expected to play in the 49ers' second preseason game Saturday, Aug. 20 at Minnesota, Matt Maiocco of NBC Sports Bay Area reports.

Trey Lance

Trey Lance

QB | SF

Tosses TD in preseason cameo

Lance completed four of five passes for 92 yards with a touchdown and no interceptions and added seven yards on one carry during the 49ers' 28-21 preseason win over the Packers on Friday night.

Brandon Aiyuk

Brandon Aiyuk

WR | SF

Sitting out Friday

Aiyuk isn't slated to play in Friday's preseason game versus the Packers, Nick Wagoner of ESPN.com reports.