No practice Wednesday
Samuel (groin) didn't practice Wednesday, Eric Branch of the San Francisco Chronicle reports.
With a 1-to-2-game absence imminent due to a groin strain, Samuel likely will log DNPs all week before the 49ers rule him out for Sunday's contest at Seattle. In his absence, the 49ers will rely on Brandon Aiyuk, Jauan Jennings, Trent Sherfield and Travis Benjamin at wide receiver, while River Cracraft and Connor Wedington are candidates to be elevated from the practice squad for game day.
More San Francisco 49ers Fantasy Football News
Ronnie Bell
WR | SF
Scores first TD of career
Bell caught both of his targets for 24 yards and a touchdown in Thursday's 30-12 win over the Giants.
Ray-Ray McCloud III
WR | SF
Not targeted in spot-start
McCloud logged 38 offensive snaps (46 percent) but was not targeted in Thursday's 30-12 win over the Giants.
Jauan Jennings
WR | SF
Gains 31 yards on TNF
Jennings caught two of three targets for 31 yards in Thursday's 30-12 win over the Giants.
Deebo Samuel
WR | SF
Emerges from win with sore ribs
Samuel's ribs are sore after a win over the Giants on Thursday, but testing didn't reveal any breaks or serious damage, Nick Wagoner of ESPN.com reports.
Elijah Mitchell
RB | SF
Season-high workload in win
Mitchell rushed 11 times for 42 yards and secured all three targets for two yards in the 49ers' 30-12 win over the Giants on Thursday night.
George Kittle
TE | SF
Best game of season Thursday
Kittle secured seven of nine targets for 90 yards in the 49ers' 30-12 win over the Giants on Thursday night.
Deebo Samuel
WR | SF
Thrives without Aiyuk in win
Samuel brought in six of 12 targets for 129 yards and a touchdown and rushed once for two yards in the 49ers' 30-12 win over the Giants on Thursday night.
Brock Purdy
QB | SF
Eclipses 300-yard mark in win
Purdy completed 25 of 37 passes for 310 yards with two touchdowns and no interceptions while rushing four times for minus-1 yard in the 49ers' 30-12 win over the Giants on Thursday night. He also fumbled once but recovered.
Christian McCaffrey
RB | SF
Efficient in Week 3 win
McCaffrey rushed 18 times for 85 yards and a touchdown and secured all five targets for 34 yards in the 49ers' 30-12 win over the Giants on Thursday night.
Ray-Ray McCloud III
WR | SF
Getting starting nod
McCloud is lining up with the 49ers' starting offense Thursday against the Giants, Matt Barrows of The Athletic reports.