Trey Lance, QB (SF)

Not practicing

Lance (knee) isn't practicing Friday, Eric Branch of the San Francisco Chronicle reports.

Jimmy Garoppolo (calf) is on track to return and start, while Lance's continued absence suggests Nate Sudfeld will need to be called up from the practice squad before Sunday's game against the Colts. The rookie QB hasn't practiced since spraining his MCL in the Week 5 loss to Arizona.

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JaMycal Hasty

JaMycal Hasty

RB | SF

Limited Wednesday

Hasty (ankle) was a limited practice participant Wednesday, Eric Branch of the San Francisco Chronicle reports.

Fred Warner

Fred Warner

LB | SF

Likely unavailable Sunday

Warner (hamstring) will likely be unavailable for Sunday's matchup against the Seahawks, Cam Inman of The San Jose Mercury News reports.

Trey Sermon

RB | SF

Sprained ankle to result in absence

Sermon has been diagnosed with an ankle sprain, and coach Kyle Shanahan said that the rookie third-round pick could land on injured reserve, Nick Wagoner of ESPN.com reports.

Jeff Wilson Jr.

Jeff Wilson Jr.

RB | SF

Resumes reserve role

Wilson had two carries for five yards and caught his lone target for two more yards in Sunday's 34-26 win over the Vikings.

Trent Sherfield

Trent Sherfield

WR | SF

Re-enters wideout rotation

Sherfield was on the field for 20 offensive snaps (27 percent) and caught his lone target for five yards in Sunday's 34-26 win over Minnesota.