Trey Lance, QB (SF)

Picks up sprained knee

Lance suffered a left knee sprain during Sunday's 17-10 loss at Arizona, leaving his status for the 49ers' next game Week 7 against the Colts, David Lombardi of The Athletic reports.

The 49ers enter their Week 6 bye with clouds hanging over both of their quarterbacks on the active roster. Jimmy Garoppolo has missed the past game and a half due to a calf contusion, but the team expects him to retake the reins of the offense as soon as he's healthy. Meanwhile, Lance, his replacement under center, has combined to completed 24 of 47 passes for 349 yards, two touchdowns and one interception and record 23 carries for 130 yards over the last two games. Coach Kyle Shanahan told Keiana Martin of the 49ers' official site that Lance's injury "should be a 1-to-2 week thing. But possibly just one." Lance is expected to be evaluated again at the end of this week, but as Shanahan mentioned the 49ers are hopeful he'll be available Week 7. Whether or not Lance is the starting quarterback remains to be seen.

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Deebo Samuel

Deebo Samuel

WR | SF

Considered 'day-to-day'

Coach Kyle Shanahan said Monday that Samuel is "day-to-day," and he hopes the wide receiver will be able to suit up for Sunday's game in Cincinnati, Cam Inman of The San Jose Mercury News reports.

Jeff Wilson Jr.

Jeff Wilson Jr.

RB | SF

Hurts knee in Week 13

Wilson sustained a knee injury during Sunday's loss in Seattle, but he should be able to practice this week, Cam Inman of The San Jose Mercury News reports.

Jauan Jennings

Jauan Jennings

WR | SF

Sticks in No. 3 role

Jennings logged 29 offensive snaps (50 percent) while catching his lone target for eight yards in Sunday's 30-23 loss to Seattle.

Elijah Mitchell

Elijah Mitchell

RB | SF

Finds end zone in loss

Mitchell carried the ball 22 times for 66 yards and a touchdown and caught all three of his targets for 18 yards in Sunday's 30-23 loss to the Seahawks.