Doubtful for Sunday

Mitchell (shoulder) is listed as doubtful for Sunday's game against the Packers, while teammate Trey Sermon (concussion) doesn't have an injury designation, Nick Wagoner of ESPN.com reports.

Sermon thus becomes the latest favorite to lead San Francisco's injury-riddled backfield, though the team isn't quite ready to make Mitchell's Week 3 absence official. GM John Lynch did sound pessimistic Friday morning when discussing the sixth-round rookie, though his return to practice Friday as a limited participant at least could be taken as a positive sign for Mitchell's chances to return in Week 4 or 5. With the Niners playing on Sunday night this week, Mitchell's fantasy managers won't want to count on the slim chance of a 'doubtful' player actually suiting up. Matt Barrows of The Athletic expects Sermon to get the start Sunday night.

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More San Francisco 49ers Fantasy Football News

Trey Lance

QB | SF

Not seen Monday

Lance (knee) was not spotted at the start of Monday's practice, Matt Maiocco of NBC Sports Bay Area reports.

Jimmy Garoppolo

QB | SF

Spotted at practice

Garoppolo (calf) is participating in the start of Monday's practice, Matt Maiocco of NBC Sports Bay Area reports.

Raheem Mostert

RB | SF

Checks in for surgery

San Francisco head coach Kyle Shanahan said Mostert will undergo surgery Tuesday to address chipped cartilage in his left knee, David Lombardi of The Athletic reports.

Jimmy Garoppolo

QB | SF

Better odds to start Week 7?

Garoppolo (calf) may have a better chance to start after the 49ers' Week 6 bye following news that Trey Lance sprained his left knee during Sunday's 17-10 loss in Arizona, David Lombardi of The Athletic reports.

Trey Lance

QB | SF

Picks up sprained knee

Lance suffered a left knee sprain during Sunday's 17-10 loss at Arizona, leaving his status for the 49ers' next game Week 7 against the Colts, David Lombardi of The Athletic reports.

Trey Sermon

RB | SF

Reverts to backup role

Sermon was only on the field for two offensive snaps (three percent) Sunday, finishing with one carry for seven yards in a 17-10 loss to Arizona.