Not seen Thursday

Mitchell (shoulder) wasn't present at the start of Thursday's practice, Matt Barrows of The Athletic reports.

After getting banged up Week 2 at Philadelphia, Mitchell was diagnosed with what coach Kyle Shanahan called a shoulder injury that's "a little worse than a stinger," per David Lombardi of The Athletic. There's still a chance Mitchell gets cleared to play Sunday night against the Packers, as does Trey Sermon, who is in the concussion protocol but was limited Wednesday. Elsewhere in the backfield, Raheem Mostert had season-ending knee surgery after Week 1, and JaMycal Hasty is slated to miss multiple games with a high-ankle sprain, leaving Trenton Cannon and Jacques Patrick as the only healthy RBs on the active roster. Meanwhile, Kerryon Johnson and Chris Thompson are stashed on the 49ers' practice squad as potential elevations.

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Raheem Mostert

RB | SF

Checks in for surgery

San Francisco head coach Kyle Shanahan said Mostert will undergo surgery Tuesday to address chipped cartilage in his left knee, David Lombardi of The Athletic reports.

Jimmy Garoppolo

QB | SF

Better odds to start Week 7?

Garoppolo (calf) may have a better chance to start after the 49ers' Week 6 bye following news that Trey Lance sprained his left knee during Sunday's 17-10 loss in Arizona, David Lombardi of The Athletic reports.

Trey Lance

QB | SF

Picks up sprained knee

Lance suffered a left knee sprain during Sunday's 17-10 loss at Arizona, leaving his status for the 49ers' next game Week 7 against the Colts, David Lombardi of The Athletic reports.

Trey Sermon

RB | SF

Reverts to backup role

Sermon was only on the field for two offensive snaps (three percent) Sunday, finishing with one carry for seven yards in a 17-10 loss to Arizona.