Brandon Aiyuk, WR (SF)

Starts, but does little

Aiyuk had one reception (two targets) for six yards in Sunday's 17-11 win over the Eagles.

Aiyuk returned to starting opposite Deebo Samuel after falling to fourth on the depth chart in Week 1. The 2020 first-round pick logged 54 percent of offensive snaps after being limited to just 30 percent last game. Despite the increase in playing time, Aiyuk didn't get much attention offensively. Head coach Kyle Shanahan claimed that Aiyuk's role reduction was due to a lingering hamstring injury, but the wideout has been a full participant in practices for two weeks now. It is unclear when Aiyuk will exit the "doghouse" and return to a prominent role on San Francisco's offense, but fantasy managers should definitely wait to deploy him until we see some evidence that he is truly back.

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Trey Lance

QB | SF

Not seen Monday

Lance (knee) was not spotted at the start of Monday's practice, Matt Maiocco of NBC Sports Bay Area reports.

Jimmy Garoppolo

QB | SF

Spotted at practice

Garoppolo (calf) is participating in the start of Monday's practice, Matt Maiocco of NBC Sports Bay Area reports.

Raheem Mostert

RB | SF

Checks in for surgery

San Francisco head coach Kyle Shanahan said Mostert will undergo surgery Tuesday to address chipped cartilage in his left knee, David Lombardi of The Athletic reports.

Jimmy Garoppolo

QB | SF

Better odds to start Week 7?

Garoppolo (calf) may have a better chance to start after the 49ers' Week 6 bye following news that Trey Lance sprained his left knee during Sunday's 17-10 loss in Arizona, David Lombardi of The Athletic reports.

Trey Lance

QB | SF

Picks up sprained knee

Lance suffered a left knee sprain during Sunday's 17-10 loss at Arizona, leaving his status for the 49ers' next game Week 7 against the Colts, David Lombardi of The Athletic reports.

Trey Sermon

RB | SF

Reverts to backup role

Sermon was only on the field for two offensive snaps (three percent) Sunday, finishing with one carry for seven yards in a 17-10 loss to Arizona.